China's Civil Aviation Administration (CAAC) has confirmed a flight from Malaysia to Beijing has lost contact.
The B777-200 aircraft departed Malaysia's capital Kuala Lumpur at 00:41 a.m. Saturday, and was expected to land in Beijing at 6:30 a.m. the same day, according to Malaysia Airlines.
The CAAC confirmed the flight number was MH370, which carries 239 people, including 12 crew members and 153 Chinese passengers.
The flight lost contact and its radar signal at 01:20 a.m. Saturday when flying over the Ho Chi Minh air traffic control area in Vietnam.
The Malaysia Airlines says it is trying to locate the flight with emergency rescue teams.